Modeling menstrual cycle length using a mixture distribution
نویسندگان
چکیده
منابع مشابه
Modeling menstrual cycle length using a mixture distribution.
In reproductive health studies, epidemiologists are often interested in examining the effects of covariates on menstrual cycle length which is a convenient, noninvasive measure of women's ovarian and reproductive function. Previous literature (Harlow and Zeger, 1991) suggests that the distribution of cycle length is a mixture of a major symmetric distribution and a component featuring a long ri...
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Prospective pregnancy studies are a valuable source of longitudinal data on menstrual cycle length. However, care is needed when making inferences of such renewal processes. For example, accounting for the sampling plan is necessary for unbiased estimation of the menstrual cycle length distribution for the study population. If couples can enroll when they learn of the study as opposed to waitin...
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This study presents a strategy for developing a mathematical model describing the concentrations of five hormones important for regulation and maintenance of the menstrual cycle. Models which correctly predict the serum levels of ovarian and pituitary hormones may assist the experimentalist by indicating directions of investigation. In addition, model simulations may be helpful for evaluating t...
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BACKGROUND Although dichlorodiphenyl trichloroethane (DDT) exposure is known to affect human endocrine function, few previous studies have investigated the effects of DDT exposure on age at menarche or menstrual cycle length. METHODS A cross sectional study was conducted to study the effects of DDT exposure on age at menarche and menstrual cycle length among 466 newly married, nulliparous fem...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2005
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxi043